Performance Assessment of FibriTimer™ Zeta-1 for PT and APTT Testing

Abstract

The FibriTimer™ Zeta-1 (called ZETA1) is a new, semi-automated multipurpose Haemostasis system, indigenously developed featuring DUAL TECHNOLOGY. ZETA1 is designed and developed by a Bangalore MedTech Startup M/S Dfine Bio-innovations Pvt Ltd, keeping in mind the needs of smaller labs. ZETA1 has not yet been evaluated in India.
The objective of this study was to evaluate the ZETA1 performance for prothrombin time (PT), activated partial thromboplastin time (APTT), and international normalized ratio (INR) under local laboratory conditions.
For within run the CV% for normal control PT and APTT were 2.42 and 4.25 and 5.91 and 2.65 for abnormal control, respectively 4. For between runs on normal control, the CV% for PT and APTT were 0.76, 0.49, 2.34, and 0.99 for Abnormal control, respectively
The correlation coefficients of INR and APTT ratio between ZETA1 and CS-1600 were 0.96 and 0.81, respectively.
Standard Error of INR and APTT Ratio were, i.e., 0.023 and 0.076, respectively.